Pearl artistic director J.R. Sullivan stages the production that will run through April 15.
The cast also includes Kern McFadden as T. Stedman Harder and Sean McNall as Mike Hogan.
According to the Pearl, "Centered on the passionate and lonely Josie Hogan and the self-destructive James Tyrone, a character modeled on O'Neill's own older brother, A Moon for the Misbegotten has been hailed as one of O'Neill's masterpieces and as one of the great works of the American stage. Having premiered in 1947, the play is a haunting exploration of despair, love, and resurrection."
For tickets, phone (212) 581-1212 or visit PearlTheatre. New York City Center Stage II is located at West 55th Street between 6th and 7th Avenues.