Created by Edward Kitsis and Adam Horowitz, the series features Sophie Lowe as Alice. Lithgow (Dirty Rotten Scoundrels, The Columnist) plays the White Rabbit, and it is reported that The Who's Roger Daltrey will voice the Caterpillar.
Sebastian Stan, who recently appeared on Broadway in Picnic, played the Mad Hatter in the pilot, but it is unlikely that he will continue with the series due to scheduling.
The show is a spin-off of ABC's "Once," and will film on the same set.
"Once Upon a Time in Wonderland" premieres Oct. 10.