Halle Berry, Jessica Biel, Zac Efron, Jon Bon Jovi, Ashton Kutcher, Til Schweiger and Hillary Swank will also appear in the film, which will follow the intertwining stories of a group of New Yorkers and their bittersweet encounters over New Year's Eve.
Garry Marshall will direct the New Line film from a screenplay by Katherine Fugate.
Academy Award nominee Breslin ("Little Miss Sunshine") appeared on Broadway in The Miracle Worker. Oscar winner De Niro ("Raging Bull," "The Godfather Part II") made his Broadway debut in Cuba & His Teddy Bear.
Emmy-nominated "Glee" star Michele counts Spring Awakening and Ragtime among her stage credits. "Sex and the City" Emmy winner Parker has appeared in Wonder of the World, Once Upon a Mattress, Sylvia and How to Succeed…, and Oscar nominee Pfeiffer ("Hairspray," "The Fabulous Baker Boys") appeared in a Public Theater production of Twelfth Night. "Modern Family" Emmy nominee Vergara appeared in Chicago.