With a new book by Charles Busch — adapted from Mark Davies’ original — Taboo will begin previews at the Plymouth Theatre Oct. 21 prior to an official opening on Nov. 13. Rosie O’Donnell and Adam Kenwright — in association with Lori E. Seid — are producing the musical, which features music and lyrics by George O’Dowd, better known as pop singer Boy George. Christopher Renshaw directs the musical, which began life at London’s Venue in January 2002. That production played its final performance April 26. Mark Dendy will choreography the Broadway mounting, and the remainder of the creative team comprises John McDaniel (musical supervision), Tim Goodchild (scenic design), Mike Nicholls and Bobby Pearce (costume design), Natasha Katz (lighting design), Jonathan Deans (sound design) and make-up and hair design (Christine Bateman).

Set in London in the early eighties, Taboo focuses on two young men: anarchic performance artist-designer Leigh Bowery and a young, rough-edged boy who becomes a surprising crossover star, Boy George. The stories of Bowery and George are told against the background of the London club Taboo.

The Plymouth Theatre is located at 236 West 45th Street. Tickets, priced between $80 and $100, will go on sale in late August through Telecharge, (212) 239-6200. For more information about the musical, visit www.tabooonbroadway.com.