The daily, one-hour show — which will originate from Los Angeles, CA — is slated to be sold to local television stations.

"Megan is a fantastic performer. A great actor and a great communicator, as all of her fans know,” said President NBC Universal Television Group Jeff Zucker. "Those skills will make her a great new addition to the daytime playing field. And I could not be more excited to have Megan still on the team."

"I'm hosting a what?" joked Mullally in a release. "Oh, okay. Well, if I am, I want it to be different and I want the viewers to play an active role and actually get something out of watching it. I think it will be fun. Jeff Zucker is going to play drums in the band.”

Best known for her role as Karen on the NBC series "Will & Grace," Mullally is remembered by theatregoers as Rosemary Pilkington in the 1995 revival of How To Succeed in Business Without Really Trying opposite Matthew Broderick. Her other stage creds include Marty in the 1994 revival of Grease. She has also performed her one woman musical, Sweetheart and numerous concert gigs at Lincoln Center, Kennedy Center, Chicago’s Goodman Theater and elsewhere.

The actress has previously hosted "Saturday Night Live" and subbed for David Letterman on CBS' "The Late Show."