Directed by Thomas Caruso, the production will officially open Oct. 6.
The cast will be led by the previously reported Annette O'Toole as Robert Eads and Jeff McCarthy as Lola. Newly announced for the musical are Jeffrey Kuhn and Todd Cerveris as well as Allison Briner, Lizzie Hagsteadt, Natalie Joy Johnson, David Lutken, Robin Skye and Joel Waggoner.
Southern Comfort features book and lyrics by Dan Collins and music by Julianne Wick Davis. The musical is described as a "uniquely American musical with a folk/bluegrass score. The musical is based on the true story of transgender friends living life openly, honestly, and courageously in rural Georgia."
The production has costume design by Patricia Doherty, lighting design by Ed McCarthy, scenic design by James Fenton and musical direction by Emily Otto.
Performances will continue through Oct. 29. Show times are Wednesday-Saturday at 7 PM.
Tickets are $18 and are available through OvationTix or online at www.cap21.org. CAP21 Black Box Theater is located at 18 West 18th Street.