Based on the lives of creators David Kohan and Max Mutchnick, "Partners," according to CBS, is "about two life-long best friends and business partners whose 'bromance' is tested when one of them is engaged to be married. Joe (Krumholtz) is an accomplished architect who leads with his head and not his heart, especially in his love life. That's in stark contrast to his gay co-worker, Louis (Urie), who is spontaneous, emotional and prone to exaggeration. Both have found joy in their love lives: Joe is newly engaged to Ali (Sophia Bush), a beautiful and sophisticated jewelry designer, while Louis is dating Wyatt (Brandon Routh), a vegan nurse who Louis insists is just a promotion away from becoming a doctor. As news of Joe's engagement settles, time will tell if their business and personal bond can adapt to the addition of two other important relationships." James Burrows directed the pilot.

Other new series include "Elementary," a contemporary take on the legendary detective Sherlock Holmes in New York City, starring Frankenstein's Jonny Lee Miller and Lucy Liu (Thursday nights at 10 PM ET); "Vegas," a drama inspired by a real-life sheriff and his battle with a powerful mobster for control of Las Vegas in the 1960s, starring Dennis Quaid and Michael Chiklis (Tuesday nights at 10 PM ET); and "Made in Jersey," starring Janet Montgomery as a smart first-year lawyer and featuring Kyle McLachlan and Tony winner Donna Murphy (Friday nights at 9 PM ET).

The freshman series will be joined by 19 returning shows, including "NCIS," "The Big Bang Theory," "Person of Interest," "2 Broke Girls," "60 Minutes," "The Amazing Race," "How I Met Your Mother," "Mike & Molly," "Hawaii Five-0" "NCIS: Los Angeles," "Survivor," "Criminal Minds," "CSI: Crime Scene Investigation," "Two and a Half Men," "CSI: NY," "Blue Bloods," "48 Hours Mystery," "The Mentalist" and "The Good Wife."

For midseason, "Undercover Boss" returns plus the new reality series "The Job," the new drama "Golden Boy" and the new comedy "Friend Me."

For more information, visit CBS.com.