Chalfy, who has appeared in Ah, Wilderness and The Rose Tattoo on Broadway, will go head to head with Pine, a veteran of Broadway's Angels in America, Bus Stop and Joe Egg, in the production, which officially opens Oct. 29 and runs through Nov. 23.
Charles Towers directs the intimate production that also features Melissa Miller as Alice Curiton (Tartuffe) and Kenneth Tigar as Saul Roth.
"A brilliant young research biologist (Chalfy) working in an obscure university lab discovers a possible cure for cancer," according to press notes. "When the dynamic director of New York's leading cancer institute (Pine) becomes his mentor and champion, he is set on a path of acclaim and prestige that could lead directly to the Nobel Prize. But the halls of science twist and turn in surprising ways, and the young doctor is suddenly thrust into the high-stakes world of medicine, money and power."
The Alley creative team includes scenic designer Bill Clark, costume designer Martha Hally, lighting designer Kevin Rigdon and sound designer Pierre Dupree.
Tickets are available by visiting www.alleytheatre.org or by calling (713) 220-5700. The Alley Theatre is located at 615 Texas Avenue in Houston, TX.