Busch's frequent collaborator Carl Andress (The Divine Sister, Die Mommie Die) will direct the March 30-April 28, 2012, run, a representative for the production confirmed to Playbill.com. Busch will star in the titular role.

Theater for the New City is also where Busch's The Divine Sister premiered in early 2010 prior to its commercial Off-Broadway run. Shanghai Moon also had its premiered there in 1999.

According to the Theater for the New City, "Lepers, whores, eunuchs centurians, evil generals, youthful poets and a beautiful redheaded widow make Charles Busch's latest comedy an event worth praying for!"

Andress previously revealed the project to Playbill.com following the New York City premiere of Kander and Ebb's The Visit, which he directed for The Actors Fund Nov. 30.

Casting and creative duties will be announced at a later date. Fans can follow the show on the official facebook page for Judith of Bethulia. Busch most recently appeared Off-Broadway in his comedy The Divine Sister, which played an extended run at the Soho Playhouse. He also appeared in a staged reading of Matthew Lombardo's Tea at Five as Katherine Hepburn as a benefit for The Ali Forney Center. His play The Tale of the Allergist's Wife, which began life at the Manhattan Theatre Club, later transferred to Broadway and was nominated for a Tony Award for Best Play. He wrote the book for the Broadway mounting of Taboo, and he also penned the screenplays for and starred in the films "Die, Mommie, Die" and "Psycho Beach Party." His noted plays include The Lady in Question, Red Scare on Sunset and the long-running Vampire Lesbians of Sodom. Busch's recent Off-Broadway appearances also include The Third Story and Die, Mommie, Die. He made his directorial film debut with "A Very Serious Person."

Tickets, priced $25, are now on sale via Smarttix.com. The Theater for the New City is located at 155 First Avenue.