Neuwirth will play herself in the Emmy-winning series, which airs on NBC-TV 8:32 PM ET; check local listings. The March 25 episode, titled "No Sex 'N' the City," also features guest appearances by Bobby Cannavale and Sharon Osbourne.

According to the official NBC website, the episode is described thusly: "Tip toeing through his budding relationship, an apprehensive Will (Eric McCormack) makes the mistake of taking Grace's (Debra Messing) advice on love, playing hard-to-get with his new pseudo-boyfriend (Bobby Cannavale). However, when his game playing causes a rift in this budding romance, Will is left questioning Grace's wisdom in matters of the heart. Meanwhile, a distraught Jack (Sean Hayes) and Karen (Megan Mullally) bravely attempt to soldier on after learning their favorite television show will be going off the air forcing them to say goodbye to their six favorite 'Friends' and a psychiatrist named Frasier Crane."

Bebe Neuwirth received Tony Awards for her performances in the revivals of Sweet Charity and Chicago. Her other Broadway credits include roles in A Chorus Line, Little Me, Dancin', Damn Yankees and Fosse. Known around the world for her Emmy Award-winning role as Lilith on the NBC series "Cheers," Neuwirth has also been seen on screen in "Summer of Sam," "Celebrity," "Liberty Heights," "The Associate," "Jumanji," "Bugsy," "The Paint Job," "Getting to Know You" and "Wild Palms."