Also in the cast will be Kurt Egyiawan, Derek Howard and Rosie Jones.
The production is directed by the Donmar's artistic director, Josie Rourke, with designs by Lucy Osborne, lighting by Oliver Fenwick, sound by Emma Laxton and music by Michael Bruce.
The play is described in press materials as a perfect tragedy of unfulfilled passion. In a new English version of the play, Man Booker Prize winner Alan Hollinghurst anatomizes the agony of love.
Duff returns to the Donmar, where she previously appeared in Days of Wine and Roses. Other theatre work includes Cause Célèbre (Old Vic), Saint Joan (National Theatre – Evening Standard & Critics' Circle Awards for Best Actress) and The Soldier’s Fortune and The Daughter-in-Law (both Young Vic). Her screen credits include "Nowhere Boy," for which she won the Evening Standard Award for Best Actress.
Cooke previously appeared at the Donmar in The Man Who Had All the Luck. His extensive work for the RSC includes Pericles, The Winter's Tale and Days of Significance. He has also worked at Shakespeare's Globe, the Lyric Hammersmith, Open Air Theatre, Regent's Park and at the National Theatre. Moore was seen onstage most recently in the Royal Court's production of Clybourne Park that subsequently transferred to the West End. Other credits include All My Sons (Apollo Theatre) and The History Boys (National Theatre and Broadway).
Rowan previously appeared at the Donmar in A Voyage Round My Father that subsequently transferred to the West End's Wyndham's. His most recent theater appearances include A Doll's House (Young Vic) and The Village Bike (Royal Court). He has appeared extensively at Shakespeare's Globe and the National Theatre.
To book tickets, contact the box office on 0844 871 7624, or visit www.donmarwarehouse.com for more details.