Karen Goodman and Kirk Simon produce and direct the half-hour series that debuted in 2010. The current season also includes episodes featuring John Guare and Bobby McFerrin.
During the episode, LuPone works with students on such songs as "I Miss the Mountains," "Change" and "Without You," among others. She also doles out her own words of wisdom about acting over dinner at Joe Allen.
Previous installments of "Masterclass" have included Edward Albee, Liv Ullman, Placido Domingo, Jacques D'Amboise and Olafur Alliason. The episodes feature artists working directly with a select group of talented students.
View a trailer for LuPone's episode below: