Performances will play the 250-seat arena-style Sheryl and Harvey White Theatre in San Diego. Opening night is Jan. 28.

Kaye won a Tony Award for playing Carlotta in The Phantom of the Opera, and was Tony-nominated for her work in Mamma Mia! and Souvenir.

Recognized as Simon's most critically acclaimed work, Lost in Yonkers received both the Pulitzer Prize and the Tony Award for Best Play. According to the Old Globe, "Set in the summer of 1942, two young brothers, Arty and Jay, are left to live with their grandmother by their financially strapped father. The boys must contend with the dominating Grandma Kurnitz who runs the family-owned candy store, their mentally-challenged Aunt Bella and her secret romance, and Uncle Louie, a small-time hood."

In addition to Kaye, the cast also features Jeffrey Bender (Louie), Steven Kaplan (Jay), Austyn Myers (Arty), Amanda Naughton (Gert), Jennifer Regan (Bella) and Spencer Rowe (Eddie).

The Lost in Yonkers creative team includes Ralph Funicello (scenic design), Alejo Vietti (costume design), Matthew McCarthy (lighting design), Paul Peterson (sound design) and Diana Moser (stage manager). Schwartz has directed several shows on Broadway including Golda's Balcony and Jane Eyre (co-directed with John Caird). He also co-directed Jane Eyre at La Jolla Playhouse in 1999. Off-Broadway credits include Bat Boy: The Musical (Lucille Lortel and Outer Critics Circle Awards, Outstanding Off Broadway Musical; Drama Desk nomination, Outstanding Director of a Musical), tick, tick…Boom! (Outer Critics Circle Award, Outstanding Off Broadway Musical; Drama Desk nomination, Outstanding Director of a Musical), Rooms: A Rock Romance, The Foreigner starring Matthew Broderick for Roundabout Theatre Company, The Castle (Outer Critics Circle nomination, Outstanding Director of a Play), Miss Julie and No Way to Treat a Lady.

For more information, visit www.TheOldGlobe.org, by phone at (619) 23-GLOBE or by visiting the box office.