Kathleen Turner directs the play, which is scheduled to officially open Feb. 7 at the Laura Pels Theatre. The limited engagement will run through April 13.
Rabe is expected to miss this weekend's shows. She is "looking forward to returning to the production as soon as possible," according to production spokespersons. Her understudy Jessica Cummings will assume the role in her absence.
Based on the recent Williamstown Theatre Festival mounting (also directed by Turner), Crimes of the Heart features a company that includes WTF stars Patch Darragh (Our Town) as Doc Porter, Jennifer Dundas (Arcadia) as Lenny Magrath, Sarah Paulson ("Studio 60 on the Sunset Strip") as Meg Magrath, Lily Rabe (Heartbreak House) as Babe Botrelle and Chandler Williams (Translations) as Barnette Lloyd with new cast member Jessica Stone (Butley) as Chick Boyle.
Crimes of the Heart is billed as "a sharply funny play about the sometimes frayed edges of sisterly bonds," according to press notes. "The Magrath sisters have trouble with men. Lonely Lenny (Dundas) never married, failed singer/actress Meg (Paulson) lost count, and the youngest, Babe (Rabe) married an abuser — and shot him. Now the sisters reunite at Old Granddaddy's home in Hazelhurst, Mississippi to face life's most absurd tragedies. Alone, each woman might call it quits. Together, they'll have the most hilarious time of their lives."
The design team includes Anna Louizos (sets), David Murin (costumes), Natasha Katz (lights) and John Gromada (sound and original compositions). For tickets to Crimes of the Heart, at the Laura Pels in the Harold and Miriam Steinberg Center for Theatre, 111 West 46th Street, call Roundabout Ticket Services at (212) 719-1300 or visit roundabouttheatre.org.