Based on the cult 1928 silent movie of the same title, William Zeffiro has penned book, music and lyrics for the tuner that will run Sept. 18-Oct. 1 at the 45th Street Theatre.

The cast includes Brooke Sunny Moriber (Follies, The Wild Party), Ann Morrison (Merrily We Roll Along, LoveMusik), Lori Hammel (Mamma Mia), John O'Creagh (The Field), Cristina Fadale (Rent), Michael Dantuono (42nd Street) and Christy McIntosh (Evil Dead: The Musical).

Mary Catherine Burke directs the musical with choreography by Sea Sullivan and music direction by David Cladwell. The creative team also includes Jesse Poleshuck (set design), Jeff Croiter (lighting design) and Sarah Maiorino (costume design).

The Road to Ruin, according to press notes, "is the cautionary tale of 15 year old 'Little Sally Canfield' – the nicest girl at Central High. When evil temptress Eve exposes Sally to her dark, delinquent side, it destroys Sally's dreams. But Soon, Sally's provincial life is surrounded by dark forces including narcissistic parents, a holier-than-thou entrepreneur, an alcoholic business woman, desperate housewives lusting after well-built young men, as well as an assortment of college athletes, strippers, prostitutes and dancing rabbits. The absurdity of America's moral conscience in 1928 is exposed through eerily familiar Corporate Christians, the self-help movement, and the bottled water health craze. But can Sally find redemption?"

A 2005 recording of Road to Ruin, featuring George S. Irving and Ann Morrison, is available from Original Cast Records. NYMF membership tickets are currently available. Single tickets go on sale Sept. 1. For more information visit NYMF.

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Running Sept. 15–Oct. 5, NYMF 2008 features musicals from around the world, culled from invitations and an open-submission process. Numerous Broadway veterans lend their talents to the new works, many of which have found commercial life Off-Broadway, and for the first time, on Broadway with [title of show].