Lythgoe, along with Kary McHoul, Charles Segars and Chad Gutstein are scouting writers for the new weekly series, which is backed by MGM TV.
"We are excited to work with Nigel, Charles and the team to identify a talented writer to create the new 'Fame,' one that reflects the struggles and joys unique to the multitude of aspiring talent today," MGM said in a statement.
A film remake of the iconic 1980 film "Fame" hit theatres in 2009. The television series premiered in 1982 and is based on the students and faculty of the New York City High School for the Performing Arts. It ran for six seasons. A stage version briefly ran Off-Broadway.