The 32-performance run will begin May 2 at the Garrick Theatre with an official opening May 7. The limited engagement will run through June 7.
Brown's last West End run at the Cambridge Theatre in 2006 in Something Wicked This Way Comes won the 2006 Laurence Olivier Award for Best Entertainment. He also previously had a West End run at the Palace Theatre in 2004.
The new show has been touring nationwide, selling out at over 80 theatres. In a press statement, Brown has commented, "For this show I wanted to return to more traditional roots of magic entertainment, and in particular the mind-readers of the 1930s. But like my other live shows, it's full of surprises, and hopefully both entertaining and thought-provoking - and of course they'll be plenty of audience participation."
Brown, who originally trained as a lawyer before starting his performing career in cafes and bars, has reached his biggest audience in TV shows, including several series of "Mind Control" for Channel 4, and "Derren Brown: Trick of the Mind," with a subsequent book entitled "Tricks of the Mind" turning into a best-seller.
The new show is directed by Andy Nyman. It runs at the Garrick Theatre, Charing Cross Road, London WC2. For tickets call 0844 412 4662.