In a video interview interview with the Los Angeles Times, Lange responded to a question about returning to theatre, saying, "Yes. Absolutely. In fact, we are going to do a production... about ten, no 12 years ago now, I did a production of what is probably my favorite play ever, of all time, Eugene O'Neill's Long Day's Journey Into Night. And I am planning on doing that sometime in the next year, year and a half, back on Broadway."

Lange previously played the role of Mary Tyrone in a 2000 production of Eugene O'Neill's familial drama in London, receiving an Olivier Award nomination for her performance as the morphine-addicted mother.

"You know, it's wonderful when you are able to create this character and then revisit it years later," she said. "Mary Tyrone is maybe my favorite character that — well, Blanche DuBois and Mary Tyrone — are my favorite characters that I have ever, ever played."

Lange made her Broadway debut in a 1992 production of A Streetcar Named Desire and returned to the stage in the 2005 revival of The Glass Menagerie.

Lange, a two-time Emmy winner, is currently starring in "American Horror Story." Her film credits include "Grey Gardens," "Big Fish," "Prozac Nation," "The Postman Always Rings Twice," "Tootsie" and "Blue Sky."