Portman, who received an Oscar for her performance in "Black Swan," met Millepied on the set of that Oscar-nominated film, which he choreographed. The couple became engaged in December 2010.
Millepied, who also provided musical staging for the Broadway-bound Hands on a Hardbody musical, and Portman have a 14-month-old son named Aleph.
Portman, who starred on Broadway in The Diary of Anne Frank, is also an Oscar nominee for "Closer." Her other film credits include "V for Vendetta," "No Strings Attached," "Thor" and "The Other Woman," among others.