Ecce Cor Meum ("Behold My Heart") is McCartney's fourth classical album since the Liverpool Oratorio was released in 1991. He worked on the piece, a commission from Magdalen College, Oxford, for more than eight years.
Anthony Smith, president of Magdalen College from 1998 to 2005, wanted "a choral piece which could be sung by young people the world over, in the same way that Handel's Messiah is."
The four-movement work for chorus and orchestra received its world premiere performance at London's Royal Albert Hall on November 3; the U.S. premiere performance is at New York's Carnegie Hall on November 14.
The singer will also sign copies of a DVD called Paul McCartney: The Space Within Us, a two-hour feature-length film of new performance footage from the 2005 "US" tour.
The signing will begin at 12 noon.