Ripley, who has been with the production since its Off-Broadway premiere at Second Stage in 2008, will headline the national tour of Next to Normal, which launches Nov. 23 in Los Angeles.

July 18 also marks the final performance of Brian d'Arcy James, who joined the Broadway cast May 17. D'Arcy James originated the role of Dan in the Off-Broadway premiere of Next to Normal, but was not part of the Broadway transfer due to his starring role in Shrek. J. Robert Spencer earned a Tony nomination for his performance in the role on Broadway.

Replacements for Ripley and d'Arcy James have not been announced. D'Arcy James already has his next Broadway booking. As previously announced, he will recreate his role in the commercial transfer of Donald Margulies' Time Stands Still this fall.

The national tour of Next to Normal will play stops in San Diego, Seattle, Des Moines, Providence, Hartford, Pittsburgh, St. Louis, St. Paul, Cleveland, Philadelphia, Charlotte and Washington, DC.

Next to Normal also features Tony Award nominee Jennifer Damiano, Kyle Dean Massey, Adam Chanler-Berat and Louis Hobson. Tom Kitt (music) and Brian Yorkey (book/lyrics) penned Next to Normal, which puts a woman's struggle with bi-polar disorder and depression center stage. Next to Normal also explores the raw emotion of a family in crisis.

The writers earned the 2010 Pulitzer Prize for Drama and the 2009 Tony Award for Best Score. Kitt was also Tony-honored for Best Orchestrations. Alice Ripley earned a Best Actress Tony Award for her portrayal of Diana Goodman.

Next to Normal arrived on Broadway in March 2009 following an Off-Broadway run at Second Stage and a regional engagement at the Arena Stage in Washington, D.C.

Next to Normal currently plays the Booth Theatre. Visit NexttoNormal.