The 21st annual awards ceremony, set to begin at 9 PM ET, features a new nomination system and new categories such as Best Cast, Best Gut-Wrenching Performance and Best On-Screen Transformation. Voting in all 12 categories is open through June 2 at MovieAwards.MTV.com.
Other presenters at the Movie Awards include Emma Stone, Kristen Stewart, Chris Hemsworth, Charlize Theron, Michael Fassbender, Mila Kunis and Mark Wahlberg.
Among the nominees are How to Succeed… and "Harry Potter" star Daniel Radcliffe, Joseph Gordon-Levitt, Ryan Gosling, Jonah Hill, Josh Hutcherson, Jennifer Lawrence, Rooney Mara, Stone, Channing Tatum, Kristin Wiig and Emma Watson.
For more information and a complete list of nominees, visit MTV.com.