"Mike and Molly" will bookend the network's Monday-night comedy block at 9:30 PM ET, following "Two and a Half Men." The new series, from "Men" and "Big Bang Theory" creator Chuck Lorre, stars Billy Gardell and Melissa McCarthy as a cop and a teacher who meet and fall in love at an OverEaters Anonymous meeting. Tony and Emmy Award winner Swoosie Kurtz ("Pushing Daisies," House of Blue Leaves, Fifth of July) and Nyambi Nyambi (Classic Stage Company's The Tempest) will also star in the sitcom. A remake of the classic cop series "Hawaii Five-O" will follow "Mike and Molly" on Mondays at 10 PM ET. The good-humored look at crime solving in a lush landscape will star Daniel Dae Kim ("Lost," Royal Albert Hall's The King and I) and Alex O'Loughlin ("The Shield").

"$#*! My Dad Says," a sitcom based on a Twitter feed about the crazy behavior of a father, will air Thursdays at 8:30 PM ET and star William Shatner ("Boston Legal," "Star Trek") as the dad. Before working in television, the Emmy Award winner appeared on Broadway in A Shot in the Dark, The World of Suzie Wong and Tamburlaine the Great.

"Blue Bloods," a drama about a family of cops airing Fridays at 10 PM ET, will star Tom Selleck ("Magnum P.I.") and Donny Wahlberg ("Band of Brothers") and will feature Tony Award winner Len Cariou (Sweeney Todd). Emmy Award winner Selleck appeared on Broadway in a 2001 revival of A Thousand Clowns.

The fifth new series on CBS' schedule, the legal drama "The Defenders," will air Wednesdays at 10 PM and stars Jim Belushi ("According to Jim") and Jerry O'Connell ("Stand By Me," "Crossing Jordan"). A "Criminal Minds" spin-off starring Academy Award winner Forest Whitaker ("The Last King of Scotland") is scheduled for mid-season.

For more information visit cbs.com.