Previews of John Crowley’s production are scheduled to begin at the New Ambassadors Theatre Nov. 25 with an official opening night on Dec. 4. The romantic comedy received its world premiere at Chicago’s Steppenwolf Theatre in April.

Campbell, who will play the role of Molly, became an international star with her film appearances in the “Scream” trilogy. She was previously seen on the London stage in Robert Altman’s heavily criticized production of Miller’s Resurrection Blues, which opened at Kevin Spacey’s Old Vic last March.

Johnston, who plays Joan, is best known for her appearances in the television series’ “3rd Rock From the Sun” and “ER.” Theatre credits include As You Like It and Portrait of a Woman for the Atlantic Theater Company, The Lights for Lincoln Center and Much Ado About Nothing for the Public Theater.

Playing the role of Joan’s husband Harry is Grammy Award winner McKean, who co-created, composed music for and starred in Rob Reiner’s comic rock movie “This Is Spinal Tap.” His most recent Broadway credits include Hairspray, in which he played Edna Turnblad; Woody Allen’s A Second Hand Memory; and the Broadway revival of The Pajama Game.

Murphy, who plays the role of Joan’s oddball brother Bean, starred in Ken Loache’s film “The Wind That Shakes the Barley,” Wes Craven’s “Red Eye,” Christopher Nolan’s “Batman Begins” and Danny Boyle’s “28 Days.” Stage credits include Disco Pigs, The Country Boy, Juno and the Paycock, Playboy of the Western World and The Shape of Things. The last Kolvenbach play directed by Crowley in London was the sibling drama On An Average Day, which premeiered at the West End’s Comedy Theatre in 2002 starring Woody Harrelson and Kyle MacLachlan. Crowley also helmed the National and Broadway productions of The Pillowman.

For more on Love Song, which is booking until March 3, call (0)970 0606627.