Eric Krebs presents the show in association with Castle Talent, Inc., M. Kilburg Reedy and Spark Productions. Performances began April 7 and opened officially April 18. By the end of its run, the show will have played 225 performances.

Using no instruments other than their voices, five vocalists known as Toxic Audio spout "complex sonic textures, rhythmic drumbeats, thumping bass lines and searing guitar-like solos in their performance of contemporary pop songs, timeless classics, jazz-scat and vocally-orchestrated original compositions," according to show materials.

Jeremy James, Shalisa James, René Ruiz, Paul Sperrazza and Michelle Mailhot Valines — who comprise Toxic Audio — make their Off-Broadway debuts in the show. Ruiz directs the work.

The show earned the 2004 Drama Desk Award for “Unique Theatrical Experience."

The design team of Toxic Audio features John A. Valines III (sound), Peter R. Feuchtwanger (scenic and lighting) and David Brooks (costumes). Toxic Audio performs at the John Houseman Theater Center, located at 450 West 42nd Street (between Ninth and Tenth Avenue).