Mark Ruffalo had previously told MTV he would be play Ned Weeks in the film and that Murphy would be involved. Murphy said at the premiere, "I think it's an important story and I think Mark Ruffalo is just beyond brilliant so I'm very excited to be directing him." He said the film would start shooting next June from a screenplay by Kramer.

Murphy was also asked about rumors that he might direct the film version of the hit musical Wicked. He said he had not made a pitch for his vision of the film but that "I’m full of admiration for everyone connected with the show."

"I love that show," Murphy added. "I've used the music of that show on 'Glee.' I think that show is about empowerment, which is what 'Glee' and 'Eat, Pray, Love' are about, so it would be an honor to be asked to [direct the adaptation]."