The play about two biracial South African brothers inaugurates the Alice Griffin Jewel Box Theater, one of three Signature venues at the new Frank Gehry-designed Pershing Square Signature Center. Opening night is Feb. 16.

Here's how the drama (nominated as Best Play for its 1985 Broadway run) is billed by Off-Broadway's Signature: "Between patchwork walls in a one-room shack, two biracial South African brothers grapple with crippling poverty and lonely isolation. Morris, the punctilious force that keeps their room tidy, is light-skinned enough to pass for white, but dark-skinned Zach feels imprisoned by his job at a whites-only park. When they find themselves on some dangerous new ground, the brothers must come face to face with the blood knot between them. Athol Fugard's revolutionary breakthrough play is a searing indictment of apartheid and one of his most celebrated works."

Blood Knot (which starred Fugard and Zakes Mokae on Broadway) is the first play in the Residency One: Athol Fugard Series. The production runs to March 11. The season also includes Fugard's My Children! My Africa! and The Train Driver.

A revival of Fugard's The Road to Mecca is currently being presented by Roundabout Theatre Company at the American Airlines Theatre. His best-known work may be the play Master Harold...and the boys. Read the recent Playbill magazine A Life in the Theatre feature on Fugard. 

Signature Theatre is under the leadership of James Houghton, founding artistic director, and Erika Mallin, executive director.

For tickets and information, visit www.signaturetheatre.com.