The limited engagement opens Feb. 18 at The Acorn Theatre in The New Group's home at Theatre Row through March 20.
A Lie of the Mind "centers on Jake, who is blinded by jealousy and rage, and believes he may have murdered his wife," as press notes explain. "While seeking refuge in the home of his abusive and unstable mother, his brother Frankie goes to investigate and finds himself caught in the confusing currents of revenge and longing."
Carradine (Dirty Rotten Scoundrels, "Dexter"), Metcalf (Brighton Beach Memoirs, "Roseanne") and Hamilton (Hurlyburly, Things We Want) are joined in the cast by Marin Ireland (After Miss Julie, reasons to be pretty), Alessandro Nivola ("Mansfield Park," "Face/Off"), Maggie Siff (Or, "Mad Men"), Frank Whaley ("Pulp Fiction," "Swimming with Sharks") and Karen Young (The Wax, "The Sopranos"). (Young appeared in the original production of the work.)
Playwright Shepard (who is also known for his work as a director and actor) earned the Pulitzer Prize for Buried Child. Other plays include Curse of the Starving Class and True West. A Lie of the Mind originally opened at the Promenade Theater in 1985.
The New Group next presents the world premiere of the new musical The Kid based on the book by Dan Savage. New Group artistic director Scott Elliott will direct Kid, which was penned by Andy Monroe (music), Jack Lechner (lyrics) and Michael Zam (book).
Tickets to A Lie of the Mind at The New Group at Theatre Row, 410 West 42nd Street (between 9th & 10th Ave.), are available by calling (212) 279-4200. For more information, visit TheNewGroup.org.