On the series Hickey plays Mark Easton, a U.S. Attorney of the Chicago district who is a presidentially appointed federal prosecutor.

Also in the cast are Jordana Spiro as Dr. Grace Devlin, Zach Gilford as Dr. Brett Robinson, William Forsythe as Constantine Alexander, Floriana Lima as Nurse Rosa "Ro" Quintero, Jaime Lee Kirchner as Dr. Olivia Watson, Tony Award nominee Željko Ivanek (Brighton Beach Memoirs) as Dr. Stafford White, James Carpinello (Rock of Ages) as Franco, Jesse Lee Soffer as Nate Devlin and Wendy Makkena (Side Man) as Daniella Devlin

Here's how Fox describes the new series: "Dr. Grace Devlin (Spiro) is a top resident at Chicago's Roosevelt Medical Center. Smart and self-assured, she's heralded as one of the country's most promising young surgeons. But family ties keep her glued to her Southside roots. To pay off her brother's life-threatening gambling debt, she makes a deal with the devil and agrees to work 'off book' for the mafia men she once despised."

"Mob Doctor" premieres Sept. 17 at 8 PM on Fox. Visit Fox.com/The-Mob-Doctor.