Tony Award winner Daniel Sullivan, who will also helm the upcoming Broadway revival of Glengarry Glen Ross, will direct the production at a Shubert theatre to be announced. Baldwin will play the role of kidnapped mobster Harold.
In a statement Baldwin said, "I have dreamed, for a long time, of doing this play with this director. It's an honor to work with Dan Sullivan in Lyle Kessler's Orphans."
Theatre, dates and additional casting will be announced at a later time.
Producers are Frederick Zollo and Robert Cole.
Orphans premiered in 1983 at Los Angeles' Matrix Theatre and won the Drama-Logue Award there. Its reputation was truly made, however, through a subsequent production at the then-young Steppenwolf Theatre Company. John Mahoney starred as Harold, with Terry Kinney and Kevin Anderson as Treat and Phillip in an explosive production directed by Gary Sinise. The show subsequently traveled to New York and London, where it helped establish Steppenwolf's signature "rock and roll" brand of theatre, as well as Kessler's status as a playwright.
Baldwin was nominated for a Tony Award in 1992 for his performance in A Streetcar Named Desire. He has also been seen on Broadway in Loot, Serious Money and Twentieth Century. The performer received an Academy Award nomination for "The Cooler" and won two Emmy Awards for his work on NBC's "30 Rock." He can currently be seen in the film adaptation of Rock of Ages.