Performances at the West Coast venue are scheduled through March 9.
Pierce based the production on the work of Nicholas Martin, who directed the Broadway staging. Martin had been announced to direct the Los Angeles production but was forced to withdraw due to scheduling conflicts.
Set in 21st century Bucks County, PA, with hints of 19th-century Russia, Vanya and Sonia and Masha and Spike, according to press notes, is a "riotous comedy with the Chekhovian set-up of a middle-aged Vanya and his stepsister, Sonia, who live together in their ancestral farmhouse, complete with a pond and a cherry orchard. Their normally quiet existence is thrown into upheaval by the surprise visit from their glamorous, movie-star sibling, Masha, and her 20-something boyfriend, Spike, the unlikely prophecies of their cleaning lady and an all too important costume party."
The production features sets by David Korins, costumes by Gabriel Berry, lighting by David Weiner and original music and sound design by Mark Bennett. The production stage manager is David S. Franklin.