Performances at the St. Louis venue continue through July 22.
The cast also features Demetria McKinney as Deena, Jenelle Lynn Randall as Lorrell, Muny veteran Ken Page as Marty, Christopher Jackson as Curtis, Karla Mosely as Michelle, Milton Craig Nealy as Jimmy and Tommar Wilson as C.C.
The production is directed by Robert Clater with choreography by Lesia Kaye.
In a previous statement Holliday said, "Dreamgirls will forever hold a very special place in my heart. I am honored and thrilled to reprise my role at the historic Muny. It's a wonderful opportunity for me to bring Effie back to life yet again and to sing under the stars before 11,000 people each and every night. A great testimony to the fact that it's never too late to dare to dream new dreams."
A native of Houston, Jennifer Holliday made her professional New York theatre debut in 1980 in the revival of Your Arms Too Short to Box With God. That role led to her Tony-winning performance in Dreamgirls, and her rendition of that show's "And I Am Telling You I'm Not Going" earned the singer-actress her first Grammy Award. She has also appeared on Broadway in the revivals of Grease! and Chicago, and her television credits include "Ellen," "Touched By an Angel" and a recurring role on "Ally McBeal." Holliday earned another Grammy Award for her recording of Duke Ellington's "Come Sunday."
Dreamgirls debuted on Broadway at the Imperial Theatre in December 1981. The musical, directed by Michael Bennett, earned 11 Tony Award nominations in 1982 and took home six, including Best Book, Best Choreography, Best Lighting and a host of acting honors.
For more information visit muny.org.