Padgett, who last played Sherrie during Rock of Ages' original run at the Brooks Atkinson Theatre, departed the 1980s-set rock musical to star in the Chicago production of the Broadway-aimed musical White Noise last spring.
She will succeed actress Rebecca Faulkenberry, who departs the production Nov. 6 to join the cast of Spider-Man Turn Off the Dark. Faulkenberry assumed the role of Sherrie when Rock of Ages transferred to the Helen Hayes Theatre March 24.
The cast of Rock of Ages also features Dan Domenech as Drew, Jeremy Woodard as Stacee Jaxx, Mitchell Jarvis as Lonny, Adam Dannheisser as Dennis, Cody Scott Lancaster as Franz, Michele Mais Justice, Josephine Rose Roberts as Regina and Paul Schoeffler as Hertz.
The ensemble includes Tessa Alves, Joey Calveri, Ericka Hunter, Tony LePage, Michael Minarik, Jennifer Rias, Andre Ward and Emily Williams.
The musical comedy Rock of Ages borrows rock hits of the 1980s to tell the story of showbiz lovers in L.A. The score includes "Every Rose Has Its Thorn," "I Wanna Know What Love Is," "Here I Go Again," "Don't Stop Believin'" and more.
Rock of Ages is written by Chris D'Arienzo, directed by Kristin Hanggi and choreographed by Kelly Devine.
The performance schedule is Monday at 8 PM, Tuesday at 7 PM, Thursday at 8 PM, Friday at 8 PM, Saturday at 2 PM and 8 PM and Sunday at 3 PM and 7:30 PM.