The cast will also include Michael K. Williams ("12 Years a Slave," "The Road"), Gloria Reuben ("Law & Order: SVU," "ER"), Mickey Sumner ("Frances Ha," "The Borgias") and K. Todd Freeman ("Teenage Mutant Ninja Turtles," "The Dark Knight"). Nelson will play Waterston's son.
"Anesthesia," which marks Nelson’s fifth directorial feature, follows the various stories of New Yorkers whose lives converge after the violent mugging of a Columbia University philosophy professor.
Holed up in a seedy motel on the edge of the Mojave Desert, two former lovers unpack the deep secrets and dark desires of their tangled relationship, passionately tearing each other apart. Led by director Daniel Aukin (Back Back Back at MTC, 4,000 Miles), Tony winner Nina Arianda (Venus in Fur at MTC, Born Yesterday) and Sam Rockwell (A Behanding in Spokane, The Way Way Back) bring an explosive intensity to Sam Shepard’s (Buried Child, True West) landmark myth of the new Wild West.