The telecast, which also features seven-time Grammy winner Pharrell Williams as the musical guest, marks Kendrick's "SNL" hosting debut.
The long-running variety show airs on NBC beginning at 11:30 PM ET; check local listings.
Seth Rogen will host "Saturday Night Live" for his third time April 12. Grammy nominee Ed Sheeran will be the evening's musical guest.
"Saturday Night Live” is produced in association with Broadway Video. The creator and executive producer is Lorne Michaels.