The musical, which has music by Alan Menken, with book and lyrics by the late Howard Ashman, will run through May 20 under the direction of Kyle Hatley. Little Shop is the final production of the Rep's 2012-13 season.
Medeiros (Broadway's Guys and Dolls) plays Seymour opposite Blanchet (Memphis) as Audrey. Michael James Leslie, whose voice was heard in the 2003 Broadway revival of Little Shop, gives voice to Audrey II.
Completing the cast are Nick Cordero (The Toxic Avenger) as Orin, Eboni Fondren as Ronette, Coleen Grate as Chiffon, Jennie Greenberry as Crystal and Gary Neal Johnson as Mushnik.
Little Shop has scenic and costume design by Meghan Raham, sound design by Joshua Horvath and lighting design by Jason Lyons.
For tickets visit KCRep.