Tierney ("News Radio," "The Good Wife") will make her Broadway debut opposite Academy Award winner Hanks. She will portray McAlary's wife Alice. Vance (Fences, Six Degrees of Separation) will portray McAlary's editor, Hap Hairston.
Tony Award-winning director George C. Wolfe will helm the production that will officially open April 1 for a limited engagement. Tickets are currently on sale through May 19.
Ephron, the late writer-director known for the screenplays to "Sleepless in Seattle," "When Harry Met Sally" and "Heartburn," authored the play about McAlary, who was a columnist for the New York Post and the Daily News.
The cast will also feature Peter Scolari (Sly Fox, Hairspray) as columnist Michael Daly, Richard Masur ("Risky Business," "And the Band Played On") as editor Jerry Nachman/editor Stanley Joyce, Christopher McDonald ("Thelma and Louise," Chicago) as lawyer Eddie Hayes, Peter Gerety ("Flight," "The Good Wife") as editor John Cotter, Michael Gaston (A Day in the Death of Joe Egg, "Mad Men") as columnist Jim Dwyer, newcomer Dustyn Gulledge as Dino Tortoricci, Deirdre Lovejoy ("The Wire," How I Learned to Drive) as reporter Louise Imerman/editor Debbie Krenek, Danny Mastrogiorgio (Golden Boy, Contact) as reporter Bob Drury and Stephen Tyrone Williams (Burning, My Children! My Africa!) as Abner Louima.
Lucky Guy will have scenic design by David Rockwell, costume design by Toni-Leslie James, sound design by Scott Lehrer, and lighting design by Jules Fisher and Peggy Eisenhauer. Projection design is by batwin + robin productions.
Hanks' numerous screen appearances include "Sleepless in Seattle," "Philadelphia," "Forrest Gump," "Cast Away," "Saving Private Ryan," "That Thing You Do" and "Cloud Atlas."
The Broadway production is produced by Colin Callender, Roy Furman, Arielle Tepper Madover, Roger Berlind, Stacey Mindich, Robert Cole and Frederick Zollo, David Mirvish, Daryl Roth, James D. Stern/Douglas L. Meyer, Scottand Brian Zeilinger, in association with Sonia Friedman Productions and The Shubert Organization.
For tickets visit Telecharge.com.