Thomas' injury occurred toward the beginning of the musical's second act, as he was transitioning from one scene to another. The singing actor was taken to the hospital, where he received stitches, and the production was stopped for approximately 10 minutes.
Reeve Carney, who created the title role and plays six performances a week, happened to be in the theatre at the time of the mishap. He stepped into the role for the remainder of the show.
Rick Miramontez, a spokesman for the show, said in a statement, "Matthew James Thomas sustained a minor injury while offstage during today's matinee performance. He is fine, and will be back in the show for his next scheduled performance on Saturday."
Numerous actors have been injured in the much-in-the-news production since rehearsals began over a year ago.
Spider-Man features creative consultation by Philip William McKinley, original direction by Tony Award winner Julie Taymor, music and lyrics by 22-time Grammy Award winners Bono and The Edge, and book co-written by Taymor, Glen Berger and Roberto Aguirre-Sacasa.
Inspired by over 40 years of Marvel comic books, Spider-Man, according to press notes, "follows the story of teenager Peter Parker, whose unremarkable life is turned upside-down when he's bitten by a genetically altered spider and wakes up the next morning clinging to his bedroom ceiling. This bullied science-geek suddenly endowed with incredible powers soon learns, however, that with great power comes great responsibility as villains put both his physical strength and strength of character to the test."