Scott Schwartz (Golda's Balcony, Mauritius) stages the production that will run through June 10 on the Neuhaus Stage.
The cast includes Chris Hutchison (Proof), Nancy Lemenager (Chicago, Movin' Out), David Andrew Macdonald (An Inspector Calls, The Green Heart), Julia Motyka (Obama 44, My Antonia) and David Rainey (Amadeus).
The production has scenic and lighting design by Kevin Rigdon, costume design by Alejo Vietti and sound design by Josh Schmidt.
What We're Up Against is presented as part of the Alley's New Play Initiative Program.
Tickets are available by visiting AlleyTheatre. The Alley Theatre is located at 615 Texas Avenue in Houston, TX.