It holds the record for the longest-running show to have ever played at the venue, by a margin of nine years, since first opening there May 14, 2002.
In a press statement, co-creators Brian May, Roger Taylor and Ben Elton commented, "We want to thank every one of the many hundreds of incredible musical theatre artists, musicians and crew with whom we've had the privilege of working at the Dominion since 2002. And of course the incredible audiences who have rewarded them with over four and a half thousand standing ovations!"
The show has also now been performed in 28 countries around the globe, and has been seen by more than 16 million people.
David Pearson, general manager of the Dominion Theatre, commented, "It has been a privilege to have hosted We Will Rock You for the past 12 years. To have the show rocking the Dominion and seeing a standing ovation night after night has been quite amazing. We wish the show every success for the future, as we now prepare to accelerate our restoration and refurbishment programme ready to welcome an exciting new production in 2015."