Highlights include a one-hour premiere of "Modern Family," set for Sept. 21 at 9 PM ET; a two-hour premiere of "Grey's Anatomy," airing Sept. 22 at 9 PM ET; and a one-hour premiere of the new series "Last Man Standing," featuring stage actors Nancy Travis (I'm Not Rappaport), Molly Ephraim (Fiddler on the Roof) and Hector Elizondo (Sly Fox), Oct. 11 at 8 PM ET.

"Revenge," featuring Henry Czerny (Arms and the Man) and Connor Paolo (The Full Monty), will follow the "Modern Family" premiere on Sept. 21 and air Wednesday nights at 10 PM.

"Charlie's Angels," starring Ramon Rodriguez (The 24 Hour Plays) as Bosley, will premiere before the "Grey's Anatomy" two-hour special Sept. 22 and is set for Thursday nights at 8 PM.

Christina Ricci (Time Stands Still) will be seen in "Pan Am" when it premieres Sept. 25. The series is set for Sunday's 10 PM ET time slot and casts Ricci as Maggie, a rebellious bohemian who turns into a buttoned- up professional for work so she can see the world.

Anna Gasteyer (Wicked, The Threepenny Opera) will guest star in "Suburgatory," premiering Sept. 28 and airing Wednesday nights at 8:30 PM ET. The comedy will focus on a single father and his daughter who move from New York City to the suburbs and have a hard time adjusting. "Private Practice," the "Grey's Anatomy" spin-off starring Taye Diggs (Rent, Chicago, Wicked), will be back Thursday nights at 10 PM when the fifth season premieres Sept. 29.

Tony Award winner Dan Fogler (The 25th Annual Putman County Spelling Bee) will star in "Man Up," as a modern man trying to get in touch with his inner tough guy, airing Tuesday nights at 8:30 PM ET and premiering Oct. 18.

"Once Upon a Time," featuring Jennifer Morrison (The Miracle Worker) and Raphael Sbarge (Voices in the Dark, Ah, Wilderness!), is the last ABC premiere for the fall and will begin Oct. 23, airing Sunday nights at 8 PM ET.

For ABC's full schedule, click here.