Directed by Jim Simpson, Heresy is the seventh Gurney world premiere produced by the Flea. It will run through Nov. 4. His plays Post Mortem, O Jerusalem, Screenplay, Mrs. Farnsworth, A Light Lunch and Office Hours also premiered there.

Here's how it's billed: "In a Government Building, in a terrifying near future, Heresy takes on the American Dream. Shall we have another cocktail or release the man who we will kill or follow to a new beginning? Heresy: men have died for less."

Joining Cathey ("The Wire"), Najimy ("Sister Act," "Hocus Pocus") and O'Toole ("A Might Wind," "Smallville") are Tommy Crawford, Steve Mellor, Danny Rivera and Ariel Woodiwiss.

Heresy has scenic design by Kate Foster, lighting design by Brian Aldous and costume design by Claudia Brown.

Gurney's plays include The Grand Manner, Scenes from American Life, The Dining Room, The Middle Ages, The Cocktail Hour, Love Letters, Sylvia, Far East, Ancestral Voices, Big Bill Indian Blood, Crazy Mary and Buffalo Gal.

The Flea Theater is located at 41 White Street (between Church and Broadway in Tribeca). For more information and tickets, visit TheFlea.org.