Chiavi in mano, a BSO commission, marks the first time that Wyner's work has been performed by the full orchestra, although other works have been premiered by the Boston Symphony Chamber Players. His recent works include Trapunto Junction, a chamber work for brass and percussion; Commedia, a piece for clarinet and piano written for Richard Stolzman and Emanuel Ax; and Horntrio, which was a finalist for the Pulitzer Prize in music in 1997.