Rob McClure, as previously reported, will reprise his Tony-nominated performance in the title role of Mrs. Doubtfire for the musical's national tour, launching from Shea's Performing Arts Center in Buffalo, New York, in September.

McClure, who created the role for the musical's Broadway 2021 premiere, will be joined by Maggie Lakis as Miranda Hillard plus the newly announced Giselle Gutierrez as Lydia Hillard, Aaron Kaburick as Frank Hillard, Nik Alexander as Andre Mayem, Leo Roberts as Stuart Dunmire, Romelda Teron Benjamin as Wanda Sellner, Cody Sawyer Braverman and Axel Bernard Rimmele as Christopher Hillard, and Emerson Mae Chan and Kennedy Alexandra Pitney as Natalie Hillard.

The ensemble will include David Hibbard, Alex Branton, Jonathan Hoover, Sheila Jones, Julie Kavanagh, Jodi Kimura, Marquez Linder, Alex Ringler, Bianca Rivera-Irions, Lannie Rubio, Neil Starkenberg, Joey Stone, Gina Ward, Lauryn Withnell, and Julia Yameen.

Along with McClure, Kaburick, Hibbard, and Kimura were also members of the Broadway company.

"It is a very rare and special event when the star of a Broadway musical takes the show on the road,"  producer Kevin McCollum said in an earlier statement. "Rob won the hearts of theatregoers and huge critical acclaim for creating one of the great musical comedy roles in Broadway history. I am thrilled that audiences across the country are not only going to be able to laugh and tear-up at Rob’s landmark performance, but also see a magical onstage chemistry with Maggie, a major talent who I first met when she starred in the national tour of Avenue Q. Our show is all about family, so to have Rob and Maggie leading this on the road, it couldn’t be more perfect."

Based on the 1993 film, Mrs. Doubtfire follows out-of-work actor Daniel Hillard, who transforms himself into a geriatric, Scottish woman so that he can be hired as a nanny for his own children after losing custody in a divorce. The work, which features a book by Karey Kirkpatrick and John O’Farrell and music and lyrics by Wayne Kirkpatrick and Karey Kirkpatrick, premiered at Seattle's 5th Avenue Theatre in 2019, making the jump to Broadway in 2021. A West End debut began in May following the musical's U.K. premiere in Manchester last fall.

Mrs. Doubtfire is directed by Jerry Zaks and features choreography by Lorin Latarro; music supervision, arrangements, and orchestrations by Ethan Popp; scenic design by David Korins; costume design by Catherine Zuber; lighting design by Philip S. Rosenberg; sound design by Brian Ronan; hair and wig design by David Brian Brown; and casting by The Telsey Office's Craig Burns.

McCollum is producing the tour in association with Work Light Productions, which also serves as executive producer and general manager.

The tour has revealed an itenerary with dates through July 2024, including stops in Washington, D.C.; Pittsburgh; Philadelphia; Chicago; Memphis; Tampa; Orlando; Los Angeles; San Francisco; and more. For a full list of cities, including performance dates, visit DoubtfireBroadway.com.