Rattlestick marketing director Sol Lieberman will moderate the discussion with actors Elizabeth Marvel, Justin Chatwin and Michael Cullen.
The work began previews Nov. 10 and opened Nov. 20 for a run through Dec. 22.
"In a house at the end of a cornfield, something almost beyond belief is happening to the Cleary family. A woman disappears, then returns talking of otherworldly beings," reads show materials. "Is she lying? Or are even darker forces at work, threatening to destroy a family already on the brink of falling apart?"
Reed Birney (Stuff Happens, Pen, Bug) is featured in the ensemble with Chatwin ("War of the Worlds," "Lost"), Cullen (Cobb, Bug) and Marvel (Seascape, Hedda Gabler).
Aguirre-Sacasa's Dark Matters was announced to play Rattlestick last season but was postponed for the downtown company's current lineup. The playwright was busy last season with the Off-Broadway run of his Based on a Totally True Story at the Manhattan Theatre Club. Other works include The Muckle Man, The Mystery Plays, Rough Magic, The Weird and The Velvet Sky. For tickets to Dark Matters at Rattlestick Playwrights Theater, 224 Waverly Place (between West 11th and Perry St.), call (212) 868-4444. For more information visit www.rattlestick.org.