In the episode that will air from 8 PM-9:30 PM ET, "Mr. Schuster (Matthew Morrison) teaches the glee club a valuable lesson about self-acceptance and embracing what makes you unique through the music of Lady Gaga," according to press notes. "Meanwhile, Lauren Zizes (Ashley Fink) and Quinn Fabray (Dianna Agron) go toe-to-toe for the prom queen crown, Ms. Pillsbury (Jayma Mays) confronts her obsessive issues, Rachel Berry (Lea Michele) struggles with a life-altering decision and Santana Lopez (Naya Rivera) has something up her sleeve that could permanently alter the glee club dynamic." The New Directions will performed the Mother Monster's latest hit, "Born This Way." In season one of "Glee," the show covered the pop diva's "Bad Romance" and "Poker Face" in a Gaga-themed episode entitled "Theatricality."

"Glee's" second season returns with all-new episodes beginning on April 19. The show airs on Fox at 8 PM ET.