Paul Morella (Angels in America at Signature) and Vanessa Lock (Nest and In the Absence of Spring at Signature) are also featured.
Helen Hayes Award winner Joe Calarco (Urinetown, Assassins and Side Show at Signature) directs the dark comedy about parents misbehaving. It runs April 10-June 24.
The French play, translated by Christopher Hampton, won the Tony Award as Best Play in 2009.
God of Carnage's DC creative team features James Kronzer (scenic design), Kathleen Geldard (costume design), Colin K. Bills (lighting design) and Matt Rowe (sound design).
Performances play Signature's 110-seat space, The ARK. Opening night is April 17. For information, visit www.signature-theatre.org.