McKean is recovering from injuries sustained on May 22 when a car struck him at the intersection of West 86th Street and Broadway on the Upper West Side.
Producer Jeffrey Richards said in a statement, "Jerry Frankel and I have worked with Michael on three previous productions, The Homecoming, The Pajama Game and Superior Donuts, and he has never missed a performance, and I understand from his team that he has never missed a performance in his career. So this is the kind of first we are reluctant to announce. He is currently in stable condition, he has a broken leg. Jerry and I look forward to working with Michael again on a future project."
The role of Mitch Graham, a reporter from the Washington Post, usually played by James Lecesne, will be played by Fred Parker.
Lecesne is making his Broadway debut in Gore Vidal's The Best Man. Previously, he has appeared Off-Broadway in Motherhood Out Loud, Boys in the Band, Word of Mouth (Drama Desk Award, Outer Critics Circle Award), Cloud 9 and One Man Band. His regional credits include I Am My Own Wife, Irma Vep (Hartford Stage). In addition to his acting work, he is also an author and activist, whose film "Trevor" received an Academy Award in 1994 for best short film. James co-founded The Trevor Project, a 24-hour suicide-prevention hotline for lesbian, gay, bisexual, transgendered, and questioning teens.
Parker is making his Broadway debut. His regional credits include Spring Storm, Mr. Marmalade, Our Town, The Glass Menagerie, As You Like It and Hamlet. The Best Man, about two presidential candidates seeking their party's nomination (and the endorsement of an ex-president) continues to Sept. 9 at the Gerald Schoenfeld Theatre.
The production has been nominated for a 2012 Tony Award for Best Revival of a Play as well as a Best Performance by an Actor in a Leading Role in a Play nomination for James Earl Jones.
Visit thebestmanonbroadway.com for information.