The new year will kick off with a battle of the sexes: Julie Bowen, Beth Behrs and Valerie Bertinelli will face off against Lester Holt, Jason Alexander and Martin Short in a series of varied games.

Also appearing this season are Sean Hayes, Olivia Wilde, Jason Sudeikis, Alison Janney, Don Cheadle, Christina Applegate, Rosie O’Donnell, Penny Marshall, Chris Colfer, Taryn Manning, Donald Faison, Kaley Cuoco, Alison Sweeney, Fred Willard, Breckin Meyer, Mark-Paul Gosselaar, Taraji P. Henson, Angela Kinsey, Jenna Elfman, Molly Shannon, Ellie Kemper, Bob Harper, Joel Madden, Nate Berkus, Erika Christensen, Michelle Trachtenberg, Mel B., Padma Lakshmi, Michael Weatherly, Yvette Nicole Brown, Anthony Anderson, Tiffani Thiessen, Pete Wentz, Adam Scott, Gary Dell’abate, Retta, Michael Chiklis, Tom Lennon, Paget Brewster, Mario Lopez, Alyssa Milano, Cobie Smulders, Taran Killam, Angie Harmon, Mark Feuerstein, Mayim Bialik and Henry Winkler.

Ray Romano, Cheryl Hines, Gavin DeGraw, Rachel Bilson, Andy Roddick and Brooklyn Decker were previously announced to appear in a holiday episode that will air Dec. 23 at 10 PM following the season finale of "The Sing-Off."

In the series, according to press notes, "two contestants are transported from their everyday lives into a once-in-a-lifetime night of fun and celebration as they step beyond the velvet rope and rub shoulders with some of their favorite celebrities and compete for the chance to win up to $25,000."

“Hollywood Game Night" is produced by Hazy Mills Productions, Mission Control Media and Universal Television. Sean Hayes, Todd Milliner, Michael Agbabian and Dwight D. Smith are executive producers.

Visit www.nbc.com/hollywood-game-night.