The Emmy-winning actress will be presented the award, given annually to an actor who fosters the "finest ideals of the acting profession," at the 18th Annual Screen Actors Guild Awards, which premieres live on TNT and TBS Jan. 29, 2012, at 8 PM ET.

Moore, according to SAG press notes, "created a new paradigm for female leads in television, won top honors for her courageous performances in film, television and on stage, produced some of the most lauded television programs of all time, and for thirty years, has served as a tireless advocate giving hope to all those afflicted with Type 1 diabetes."

Screen Actors Guild National President Ken Howard said in a statement, "Mary Tyler Moore won our hearts as Laura Petrie and Mary Richards, our respect as her production company became synonymous with quality television, our awe as she tackled difficult subject matter in film and on Broadway, and our admiration she turned her public recognition into a catalyst to draw attention to critical and deeply personal health and social issues.  She truly embodies the spirit behind SAG’s Life Achievement Award, and we are honored to proclaim her as its 48th recipient."

Screen Actors Guild is the nation’s largest labor union representing working actors.

For more information visit www.sagawards.org.